A Practical Guide to the Histology of the Mouse by Cheryl L. Scudamore PDF

By Cheryl L. Scudamore

ISBN-10: 1119941202

ISBN-13: 9781119941200

A functional advisor to the Histology of the Mouse provides a full-colour atlas of mouse histology. Mouse versions of disorder are used greatly in biomedical examine with many hundreds of thousands of recent types being generated every year. entire phenotypic research of all of those versions can take advantage of histologic evaluation of the tissues.

This ebook is aimed toward veterinary and scientific pathologists who're strange with mouse tissues and scientists who desire to evaluation their very own mouse versions. It offers functional information at the assortment, sampling and research of mouse tissue samples in an effort to maximize the knowledge that may be received from those tissues. in addition to illustrating the conventional microscopic anatomy of the mouse, the booklet additionally describes and explains the typical anatomic diversifications, artefacts linked to tissue assortment and history lesions to assist the scientist to differentiate those alterations from experimentally- brought on lesions.

This may be a vital bench-side spouse for researchers and practitioners trying to find an available and well-illustrated consultant to mouse pathology.

  • Written through skilled pathologists and particularly adapted to the wishes of scientists and histologists
  • Full color throughout
  • Provides recommendation on sampling tissues, necropsy and recording data
  • Includes universal anatomic adaptations, history lesions and artefacts for you to support non-experts comprehend no matter if histologic diversifications noticeable are a part of the conventional heritage or relating to their experimental manipulation

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Extra resources for A Practical Guide to the Histology of the Mouse

Sample text

In these cases, histopathological examination of the nasal turbinates often results in the diagnosis of a severe purulent rhinitis. 26 Merkel’s diverticulum is a congenital defect which causes an out pouching of the small intestine generally in the region of the jejunum. 27 Excessive accumulation of gas in the gastrointestinal tract of a mouse suffering from purulent rhinitis. enlargement and colour changes. The mesenteric lymph nodes may demonstrate the presence of lymphoma, which is very common in certain strains of mice.

1996) Cutaneous changes in commonly used inbred mouse strains and mutant stocks, in Pathobiology of the Aging Mouse (eds U. M. C. ), ISlI Press, Washington, DC, pp. 325–337. W. (2006) Histopathology of the spleen. Toxicologic Pathology 34, 466–503. C. et al. A retrospective analysis of background lesions and tissue accountability for male accessory sex organs in Fischer-344 rats. Toxicologic Pathology 29, 467–478. Taradach, C. and Greaves, P. (1984) Spontaneous eye lesions in laboratory animals: incidence in relation to age.

A. et al. (2010) A comparison of fixation methods on lung morphology in a murine model of emphysema. American Journal of Physiology: Lung Cellular and Molecular Physiology 299, L843–851. M. et al. (2012) Assessing cervical dislocation as a humane euthanasia method in mice. Journal of the American Association for Laboratory Animal Science 51, 352–356. A. (2000) The mammary pathology of genetically engineered mice: the consensus report and recommendations from the Annapolis meeting. Oncogene 19, 968–988.

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A Practical Guide to the Histology of the Mouse by Cheryl L. Scudamore

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