By Gianfranco Donelli (eds.)
The sequence will offer microbiologists, hygienists, epidemiologists and infectious illnesses experts with well-chosen contributed volumes containing up-to-date info within the parts of uncomplicated and utilized microbiology related to proper matters for public overall healthiness, together with bacterial, fungal and parasitic infections, zoonosis and anthropozoonosis, environmental and foodstuff microbiology.
The expanding possibility of the multidrug-resistant microorganisms and the comparable host immune reaction, the recent techniques for the therapy of biofilm-based, acute and persistent microbial infections, in addition to the advance of recent vaccines and extra efficacious antimicrobial medications to avoid and deal with human and animal infections might be additionally reviewed during this sequence within the mild of the latest achievements in those fields.
Special awareness can be dedicated to the quick diffusion around the world of the hot findings of the main complex translational researches performed within the diverse fields of microbiological sciences, with the purpose to advertise a instructed validation and move at scientific point of the main promising experimental results.
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Extra resources for Advances in Microbiology, Infectious Diseases and Public Health: Volume 1
Cellulose J 21:3767–3779 Malic S, Hill KE, Playle R, Thomas DW, Williams DW (2011) In vitro interaction of chronic wound bacteria in biofilms. J Wound Care 20(12):569–570 Merritt JH, Kadouri DE, O’Toole GA (2011) Growing and analyzing static biofilms. Curr Protoc Microbiol 22:1–8 Miller KG, Tran PL, Haley CL, Kruzek C, ColmerHamood JA, Myntti M, Hamood AN (2014) Next science wound gel technology, a novel agent that inhibits biofilm development by gram-positive and gram-negative wound pathogens.
Pagano, A. Fusco, and G. it 33 34 V. Vastano et al. Keywords L. plantarum LM3 • Adhesins • Immunomodulation • Biofilm 1 Introduction The intestinal epithelium, once considered simply a physical barrier, is now considered a regulator of intestinal immune homeostasis. In this regard, the interaction of epithelial cells with the microbiota has the key role of mediator of the cross-talk between the epithelium and other cell types in the mucosa (Darab et al. 2011). Indeed, intestinal epithelium cells (IECs) express a wide variety of pattern recognition receptors (PRR) to detect the presence of microbes.
Treatment of Caco2 cells with the LM3-CC1 strain failed to induce TLR-2 expression as monitored up to 24 h exposure (Fig. 1, panel A). 6 fold after 3 h exposure to LM3 wild type, and decreased to basal levels upon 24 h exposure (Fig. 1, panel B); L. plantarum LM3-CC1 stimulated a similar level of TLR-4 expression in Caco-2 cells (Fig. 1, panel B). 2 L. plantarum LM3-Induced HBD-2 Expression in Caco2 Cells To determine whether human colon epithelial cell lines constitutively express β-defensins, RNAs from un-stimulated Caco-2 cells were analysed by Real Time PCR using HBD-1, HBD-2 and HBD-3 specific primers.
Advances in Microbiology, Infectious Diseases and Public Health: Volume 1 by Gianfranco Donelli (eds.)